Riboflavin contributes to: normal energy-yielding metabolism, normal functioning of the nervous system, normal metabolism of iron and reduction of tiredness and fatigueVitamin B2 contributes to the maintenance of: normal mucous membranes, normal red blood cells, normal skin and normal vision. Riboflavin is an antioxidant – it contributes to the protection of cells from oxidative stress.400mg dose is recommended by NICE (National Institute for Health and Care Excellence) as off-label vitamin use to reduce the number and severity of migraines.